THAP11 antibody (C-Term)

Catalog No. ABIN6991944

Product Details anti-THAP11 Antibody

Target: THAP11 (THAP Domain Containing 11 (THAP11))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THAP11 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: THAP11 antibody is human, mouse and rat reactive.

Purification: THAP11 antibody is affinity chromatography purified via peptide column.

Immunogen: THAP11 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human THAP11. The immunogen is located within the last 50 amino acids of THAP11.

Isotype: IgG

Application Details

Application Notes: THAP11 antibody can be used for detection of THAP11 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: THAP11 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: THAP11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for THAP11

Target: THAP11 (THAP Domain Containing 11 (THAP11))

Alternative Name: THAP11 (THAP11 Products)

Synonyms: CTG-B43a antibody, CTG-B45d antibody, RONIN antibody, 2810036E22Rik antibody, AB041579 antibody, Ronin antibody, wu:fa14e04 antibody, wu:fc33b05 antibody, zgc:65871 antibody, zgc:76876 antibody, THAP domain containing 11 antibody, THAP domain containing 11 L homeolog antibody, THAP domain-containing protein 11 antibody, Thap11 antibody, thap11.L antibody, THAP11 antibody, thap11 antibody, tha11 antibody

Background: The THAP domain-contining protein 11 (THAP11), also known as Ronin, is an essential factor involved in embryonic stem (ES) cell pluripotency and cell growth (1). THAP 11 contains a THAP domain, a conserved DNA-binding domain common to many proteins associated with chromatin modification and gene expression silencing, and has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases (2). THAP11 can also negatively regulate CD44 v6 expression through its interaction with the poly(rC) binding protein PCBP1 (3).

Molecular Weight: Predicted: 35 kDa

Observed: 38 kDa

Gene ID: 57215

NCBI Accession: NP_065190

UniProt: Q96EK4