IL1F10 antibody (C-Term)

Catalog No. ABIN6991914

Product Details anti-IL1F10 Antibody

Target: IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1F10 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: IL-1F10 antibody is human, mouse and rat reactive. Two isoforms of IL-1F10 exist.

Purification: IL-1F10 antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-IL-1F10 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human IL-1F10. The immunogen is located within the last 50 amino acids of IL-1F10.

Isotype: IgG

Application Details

Application Notes: WB: 1 μ,g/mL, IHC: 5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: IL-1F10 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: IL-1F10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for IL1F10

Target: IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))

Alternative Name: IL-1F10 (IL1F10 Products)

Synonyms: FIL1-theta antibody, IL-1HY2 antibody, IL-38 antibody, IL1-theta antibody, IL1HY2 antibody, interleukin 1 family, member 10 antibody, interleukin 1 family member 10 antibody, Il1f10 antibody, IL1F10 antibody

Background: The cytokine IL-1 is responsible for initiating a variety of activities through the activation of transcription factors, NF-kappa B and AP-1, thereby promoting host response to injury or infection (1). IL-1F10 (Interleukin-1 family member 10), also known as FIL1T, IL1HY2 or FKSG75, is highly expressed in the skin, spleen and proliferating B-cells of the tonsil (2). IL-1F10 binds soluble IL-1 receptor type 1, and is one of nine Interleukin 1 families clustered on chromosome 2, where it is thought to participate in the regulation of adapted and innate immune responses (3). IL-1F10 and IL-1RN polymorphisms may play an important role in the susceptibility to developing rheumatoid arthritis (4).

Molecular Weight: Predicted: 17kD

Observed: 17 kD kDa

Gene ID: 84639

NCBI Accession: NP_775184

UniProt: Q8WWZ1