PHF14 antibody (N-Term)

Catalog No. ABIN6991907

Product Details anti-PHF14 Antibody

Target: PHF14 (PHD Finger Protein 14 (PHF14))

Binding Specificity: AA 210-260, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF14 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: PHF14 antibody is human, mouse and rat reactive. Multiple isoforms of PHF14 are known to exist.

Purification: PHF14 Antibody is affinity chromatography purified via peptide column.

Immunogen: PHF14 antibody was raised against a 19 amino acid peptide near the amino terminus of human PHF14. The immunogen is located within amino acids 210 - 260 of PHF14 .

Isotype: IgG

Application Details

Application Notes: PHF14 antibody can be used for detection of PHF14 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PHF14 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: PHF14 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for PHF14

Target: PHF14 (PHD Finger Protein 14 (PHF14))

Alternative Name: PHF14 (PHF14 Products)

Synonyms: 1110001C23Rik antibody, 4932409F11Rik antibody, 5730446A07Rik antibody, AA623952 antibody, AV297001 antibody, mKIAA0783 antibody, PHD finger protein 14 antibody, PHF14 antibody, Phf14 antibody

Background: PHF14, a novel plant homology domain (PHD) transcription factor, controls the proliferation of mesenchymal cells by regulating PDGFR alpha expression in embryonic development (1). PHD finger transcription factors are concerned with transcriptional regulation by interacting with modified histones (2), and dysregulation of several genes encoding PHD finger transcription factors, such as ING1 and RBP2, has been found in human cancer diseases suggesting these factors have an important role for cancer cell proliferation. PHF14 is a potential target for new treatments of lung fibrosis (1, 3).

Molecular Weight: Predicted: 98 kDa

Observed: 100kDa

Gene ID: 9678

NCBI Accession: NP_055475

UniProt: O94880