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ERAP2 antibody (N-Term)

ERAP2 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991900
  • Target See all ERAP2 Antibodies
    ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))
    Binding Specificity
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 110-160, N-Term
    Reactivity
    • 20
    • 2
    • 1
    • 1
    Human
    Host
    • 15
    • 3
    • 2
    Rabbit
    Clonality
    • 19
    • 1
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERAP2 antibody is un-conjugated
    Application
    • 10
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificity
    ERAP2 antibody is human reactive. Multiple isoforms of ERAP2 are known to exist. ERAP2 antibody is predicted to not cross-react with ERAP1.
    Purification
    ERAP2 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    ERAP2 antibody was raised against a 17 amino acid peptide near the amino terminus of human ERAP2. The immunogen is located within amino acids 110 - 160 of ERAP2 .
    Isotype
    IgG
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  • Application Notes
    ERAP2 antibody can be used for detection of ERAP2 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    ERAP2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    ERAP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))
    Alternative Name
    ERAP2 (ERAP2 Products)
    Synonyms
    L-RAP antibody, LRAP antibody, ERAP2 antibody, zgc:172163 antibody, endoplasmic reticulum aminopeptidase 2 antibody, ERAP2 antibody, erap2 antibody
    Background
    The endoplasmic reticulum (ER) aminopeptidase 2 (ERAP2), a member of the peptidase M1 family, like the related protein ERAP1, plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides (1,2). Like ERAP1, ERAP2 is localized to the lumen of the ER and is thought to associate with ERAP1 as a heterodimer (1). Both ERAP1 and ERAP2 have been linked to several human diseases ranging from infections to autoimmunity and cancer, and may play a role in the innate immune response (reviewed in 3).
    Molecular Weight
    Predicted: 106 kDa

    Observed: 120kDa
    Gene ID
    64167
    NCBI Accession
    NP_071745
    UniProt
    Q6P179
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