TLX2 antibody (N-Term)

Catalog No. ABIN6991867

Product Details anti-TLX2 Antibody

Target: TLX2 (T-Cell Leukemia Homeobox 2 (TLX2))

Binding Specificity: AA 20-70, N-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: TLX2 antibody is predicted to not cross-react with other TLX proteins.

Purification: TLX2 Antibody is affinity chromatography purified via peptide column.

Immunogen: TLX2 antibody was raised against an 18 amino acid peptide near the amino terminus of human TLX2. The immunogen is located within amino acids 20 - 70 of TLX2.

Isotype: IgG

Application Details

Application Notes: TLX2 antibody can be used for detection of TLX2 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TLX2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TLX2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for TLX2

Target: TLX2 (T-Cell Leukemia Homeobox 2 (TLX2))

Alternative Name: TLX2 (TLX2 Products)

Synonyms: Enx antibody, Hox11L.1 antibody, Hox11l1 antibody, NCX antibody, Ncx1 antibody, Tlx1l1 antibody, Tlx1l2 antibody, HOX11L1 antibody, Tlx-3a antibody, hox11l antibody, tlx3a antibody, tlxA antibody, T cell leukemia, homeobox 2 antibody, T-cell leukemia homeobox 2 antibody, T-cell leukemia, homeobox 2 antibody, Tlx2 antibody, TLX2 antibody, tlx2 antibody

Background: TLX2 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX2, also known as homeobox11-like 1 (HOX11L1), is a DNA-binding nuclear transcription factor that appears to be crucial for the development of the peripheral nervous system. TLX2 is a downstream target of regulation by both PHOX2A and PHOX2B proteins during intestinal neuronal differentiation. In humans, loss-of-function of TLX2 may play a role in tumorigenesis of gastrointestinal stromal tumors.

Molecular Weight: Predicted: 31 kDa

Observed: 30 kDa

Gene ID: 3196

NCBI Accession: NP_057254

UniProt: O43763