KANK2 antibody (C-Term)

Catalog No. ABIN6991852

Product Details anti-KANK2 Antibody

Target: KANK2 (KN Motif and Ankyrin Repeat Domains 2 (KANK2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KANK2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Two alternatively spliced transcript variants encoding different isoforms have been identified.

Purification: KANK2 Antibody is affinity chromatography purified via peptide column.

Immunogen: KANK2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human KANK2 . The immunogen is located within the last 50 amino acids of KANK2.

Isotype: IgG

Application Details

Application Notes: KANK2 Antibody can be used for detection of KANK2 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: KANK2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: KANK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for KANK2

Target: KANK2 (KN Motif and Ankyrin Repeat Domains 2 (KANK2))

Alternative Name: KANK2 (KANK2 Products)

Synonyms: ANKRD25 antibody, MXRA3 antibody, SIP antibody, AI504612 antibody, Ankrd25 antibody, BC010245 antibody, KN motif and ankyrin repeat domains 2 antibody, KANK2 antibody, Kank2 antibody

Background: KANK2 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK2 (KN motif and ankyrin repeat domain-containing protein 2), was initially identified as a steroid receptor coactivator (SRC) interacting protein (SIP) that could sequester steroid receptor coactivators in the cytoplasm. More recent experiments have shown that while KANK2 is widely expressed, in kidney podocytes, KANK2 localizes to foot processes, suggesting that KANK2 may contribute to controlling actin dynamics in podocyte foot processes.

Molecular Weight: Predicted: 95 kDa

Observed: 102 kDa

Gene ID: 25959

NCBI Accession: NP_056308

UniProt: Q63ZY3