MTERFD1 antibody (C-Term)

Catalog No. ABIN6991840

Product Details anti-MTERFD1 Antibody

Target: MTERFD1 (MTERF Domain Containing 1 (MTERFD1))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTERFD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: At least three isoforms of MTERFD1 are known to exist. MTERFD1 antibody is predicted to not cross-react with other MTERFD protein family members.

Purification: MTERFD1 Antibody is affinity chromatography purified via peptide column.

Immunogen: MTERFD1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human MTERFD1 . The immunogen is located within the last 50 amino acids of MTERFD1.

Isotype: IgG

Application Details

Application Notes: MTERFD1 Antibody can be used for detection of MTERFD1 by Western blot starting at 1 μ,g/mL. Antibody can also be used for Immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: MTERFD1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: MTERFD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for MTERFD1

Target: MTERFD1 (MTERF Domain Containing 1 (MTERFD1))

Alternative Name: MTERFD1 (MTERFD1 Products)

Synonyms: zgc:92270 antibody, mTERF3 antibody, 2410017I18Rik antibody, MTERF3 antibody, Cgi12 antibody, mitochondrial transcription termination factor 3 antibody, MTERF domain containing 1 antibody, mterf3 antibody, MTERF3 antibody, Mterfd1 antibody, Mterf3 antibody

Background: MTERFD1 Antibody: Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD1 is composed of three leucine zippers that form a three-stranded coiled-coil that binds to DNA. It binds promoter DNA and acts as a mitochondrial transcription regulator. It has been suggested that only the phosphorylated form of MTERFD1 has transcription termination activity. A closely related mTERF family member, MTERFD3, is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription.

Molecular Weight: Predicted: 46 kDa

Observed: 42 kDa

Gene ID: 51001

NCBI Accession: NP_057026

UniProt: Q96E29