IL17RE antibody (AA 230-280)

Catalog No. ABIN6991804

This Rabbit Polyclonal antibody specifically detects IL17RE in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for IL17RE antibody (AA 230-280) (ABIN6991804)

Target: IL17RE (Interleukin 17 Receptor E (IL17RE))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17RE antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL17RE Antibody

Binding Specificity: AA 230-280

Purification: IL-17RE Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal IL-17RE antibody was raised against a 16 amino acid peptide near the center of human IL-17RE. The immunogen is located within amino acids 230 - 280 of IL-17RE.

Isotype: IgG

Application Details

Application Notes: IL-17RE antibody can be used for detection of IL-17RE by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: IL-17RE Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: IL-17RE antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for IL17RE

Target: IL17RE (Interleukin 17 Receptor E (IL17RE))

Alternative Name: IL-17RE

Background: IL-17RE Antibody: The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.

Molecular Weight: Predicted: 78 kDa

Gene ID: 132014

NCBI Accession: NP_705616

UniProt: Q8NFR9