SGSM2 antibody (AA 650-700)

Catalog No. ABIN6991754

Product Details anti-SGSM2 Antibody

Target: SGSM2 (Small G Protein Signaling Modulator 2 (SGSM2))

Binding Specificity: AA 650-700

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGSM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: Multiple isoforms of SGSM2 are known to exist. SGSM2 antibody is predicted to not cross react with other SGSM family proteins.

Purification: SGSM2 Antibody is affinity chromatography purified via peptide column.

Immunogen: SGSM2 antibody was raised against an 18 amino acid synthetic peptide near the center of human SGSM2. The immunogen is located within amino acids 650 - 700 of SGSM2.

Isotype: IgG

Application Details

Application Notes: SGSM2 antibody can be used for detection of SGSM2 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SGSM2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SGSM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SGSM2

Target: SGSM2 (Small G Protein Signaling Modulator 2 (SGSM2))

Alternative Name: SGSM2 (SGSM2 Products)

Synonyms: RUTBC1 antibody, D630003G22Rik antibody, R74628 antibody, Rutbc1 antibody, mKIAA0397 antibody, small G protein signaling modulator 2 antibody, SGSM2 antibody, Sgsm2 antibody

Background: SGSM2 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM2 is a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.

Molecular Weight: 116 kDa

Gene ID: 9905

NCBI Accession: NP_055668

UniProt: O43147