Myc Target 1 antibody (C-Term)
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- Target See all Myc Target 1 (MYCT1) Antibodies
- Myc Target 1 (MYCT1)
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Myc Target 1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- At least two isoforms of MYCT1 are known to exist, this antibody will detect both isoforms.
- Purification
- MYCT1 Antibody is affinity chromatography purified via peptide column.
- Immunogen
- MYCT1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1. The immunogen is located within the last 50 amino acids of MYCT1.
- Isotype
- IgG
- Top Product
- Discover our top product MYCT1 Primary Antibody
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- Application Notes
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MYCT1 antibody can be used for detection of MYCT1 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- MYCT1 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,4 °C
- Storage Comment
- MYCT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- Myc Target 1 (MYCT1)
- Alternative Name
- MYCT1 (MYCT1 Products)
- Synonyms
- MYCT1 antibody, MGC147166 antibody, si:dkey-12h9.2 antibody, MTLC antibody, 1110020B04Rik antibody, AI225941 antibody, AI642973 antibody, Mtmc1 antibody, myc target 1 antibody, MYC target 1 antibody, myc target 1a antibody, MYCT1 antibody, myct1 antibody, myct1a antibody, Myct1 antibody
- Background
- MYCT1 Antibody: MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
- Molecular Weight
- 26 kDa
- Gene ID
- 80177
- NCBI Accession
- NP_079383
- UniProt
- Q8N699
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