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TET3 antibody (C-Term)

TET3 Reactivity: Human, Mouse, Rat WB, ELISA, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991743
  • Target See all TET3 Antibodies
    TET3 (Tet Methylcytosine Dioxygenase 3 (TET3))
    Binding Specificity
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 1520-1570, C-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 13
    • 10
    • 1
    Rabbit
    Clonality
    • 15
    • 9
    Polyclonal
    Conjugate
    • 20
    • 2
    • 1
    • 1
    This TET3 antibody is un-conjugated
    Application
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    At least three isoforms of TET3 are known to exist. TET3 antibody is predicted to not cross react with other TET proteins.
    Purification
    TET3 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    TET3 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TET3. The immunogen is located within amino acids 1520 - 1570 of TET3.
    Isotype
    IgG
    Top Product
    Discover our top product TET3 Primary Antibody
  • Application Notes
    TET3 antibody can be used for detection of TET3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    TET3 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    TET3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    TET3 (Tet Methylcytosine Dioxygenase 3 (TET3))
    Alternative Name
    TET3 (TET3 Products)
    Synonyms
    B430006D22Rik antibody, BC037432 antibody, D230004J03Rik antibody, tet methylcytosine dioxygenase 3 antibody, Tet3 antibody, TET3 antibody
    Background
    TET3 Antibody: TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.
    Molecular Weight
    183 kDa
    Gene ID
    200424
    NCBI Accession
    NP_001274420
    UniProt
    O43151
    Pathways
    Warburg Effect
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