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NDFIP1 antibody (N-Term)

NDFIP1 Reactivity: Human, Mouse ELISA, WB, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991731
  • Target See all NDFIP1 Antibodies
    NDFIP1 (Nedd4 Family Interacting Protein 1 (NDFIP1))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 40
    • 14
    • 11
    Human, Mouse
    Host
    • 38
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 40
    • 2
    Polyclonal
    Conjugate
    • 16
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NDFIP1 antibody is un-conjugated
    Application
    • 24
    • 24
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    NDFIP1 antibody is predicted to not cross-react with NDFIP2.
    Purification
    NDFIP1 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    NDFIP1 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human NDFIP1. The immunogen is located within the first 50 amino acids of NDFIP1.
    Isotype
    IgG
    Top Product
    Discover our top product NDFIP1 Primary Antibody
  • Application Notes
    NDFIP1 antibody can be used for detection of NDFIP1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    NDFIP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    NDFIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    NDFIP1 (Nedd4 Family Interacting Protein 1 (NDFIP1))
    Alternative Name
    NDFIP1 (NDFIP1 Products)
    Synonyms
    zgc:55546 antibody, wu:fc17e11 antibody, n4wbp5 antibody, MGC108163 antibody, ndfip1 antibody, NDFIP1 antibody, N4WBP5 antibody, 0610010M22Rik antibody, N4wbp5 antibody, Nedd4 family interacting protein 1 antibody, Nedd4 WW domain-binding protein 5 antibody, ndfip1 antibody, NDFIP1 antibody, n4wbp5 antibody, Ndfip1 antibody
    Background
    NDFIP1 Antibody: The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.
    Molecular Weight
    24 kDa
    Gene ID
    80762
    NCBI Accession
    NP_085048
    UniProt
    Q9BT67
    Pathways
    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Negative Regulation of Transporter Activity
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