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PRC1 antibody (AA 350-400)

PRC1 Reactivity: Human, Mouse, Rat WB, ELISA, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991683
  • Target See all PRC1 Antibodies
    PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
    Binding Specificity
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 350-400
    Reactivity
    Human, Mouse, Rat
    Host
    • 22
    • 3
    Rabbit
    Clonality
    • 22
    • 3
    Polyclonal
    Conjugate
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PRC1 antibody is un-conjugated
    Application
    • 11
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.
    Purification
    PRC1 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    PRC1 antibody was raised against a 19 amino acid synthetic peptide near the center of human PRC1. The immunogen is located within amino acids 350 - 400 of PRC1.
    Isotype
    IgG
    Top Product
    Discover our top product PRC1 Primary Antibody
  • Application Notes
    PRC1 antibody can be used for detection of Prc1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PRC1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    PRC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
    Alternative Name
    PRC1 (PRC1 Products)
    Synonyms
    cb212 antibody, prc1 antibody, prc1l antibody, zgc:55982 antibody, zgc:86918 antibody, MGC68845 antibody, zgc:55664 antibody, ase1 antibody, ASE1 antibody, D7Ertd348e antibody, protein regulator of cytokinesis 1 antibody, protein regulator of cytokinesis 1a antibody, protein regulator of cytokinesis 1 S homeolog antibody, protein regulator of cytokinesis 1b antibody, PRC1 antibody, prc1a antibody, prc1.S antibody, prc1b antibody, CNC07120 antibody, prc1 antibody, Prc1 antibody
    Background
    PRC1 Antibody: PRC1 (Protein Regulator of Cytokinesis 1) is a key regulator of cytokinesis and has been identified as a substrate for several cyclin-dependent kinases (CDKs). High levels of PRC1 expression occurs during S and G2/M and drops dramatically after mitosis exit and G1 entry. It is located in the nucleus during interphase and binds to the midzone of mitotic spindles during anaphase and is localized to the cell midbody during cytokinesis. Depletion of PRC1 has been shown to prevent cellular cleavage, but it has no effect on nuclear division, demonstrating the importance of PRC1 in mitosis.
    Gene ID
    9055
    NCBI Accession
    NP_003972
    UniProt
    O43663
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