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VKORC1 antibody (N-Term)

VKORC1 Reactivity: Human, Mouse WB, ELISA, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991675
  • Target See all VKORC1 Antibodies
    VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))
    Binding Specificity
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    N-Term
    Reactivity
    • 22
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 22
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    This VKORC1 antibody is un-conjugated
    Application
    • 18
    • 17
    • 17
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    VKORC1 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    VKORC1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human VKORC1. The immunogen is located within the first 50 amino acids of VKORC1.
    Isotype
    IgG
    Top Product
    Discover our top product VKORC1 Primary Antibody
  • Application Notes
    VKORC1 antibody can be used for detection of VKORC1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    VKORC1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    VKORC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))
    Alternative Name
    VKORC1 (VKORC1 Products)
    Synonyms
    MGC89620 antibody, BP1071 antibody, CG33544 antibody, Dmel\\CG33544 antibody, HDC06808 antibody, VKORC1 antibody, EDTP308 antibody, IMAGE3455200 antibody, MST134 antibody, MST576 antibody, VKCFD2 antibody, VKOR antibody, D7Wsu86e antibody, vitamin K epoxide reductase complex, subunit 1 antibody, vitamin K epoxide reductase complex subunit 1 antibody, Vitamin-K epoxide reductase antibody, VKORC1 antibody, vkorc1 antibody, Vkor antibody, Vkorc1 antibody
    Background
    VKORC1 Antibody: Vitamin K epoxide reductase complex subunit 1 (VKORC1) is the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form which is essential for blood clotting. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is VKORC1 that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance.
    Gene ID
    79001
    NCBI Accession
    NP_076869
    UniProt
    Q9BQB6
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