ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
Purification
RILP Antibody is affinity chromatography purified via peptide column.
Immunogen
RILP antibody was raised against an 18 amino acid synthetic peptide near the center of human RILP. The immunogen is located within amino acids 110 - 160 of RILP.
RILP
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
RILP antibody can be used for detection of RILP by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
RILP Antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C,4 °C
Storage Comment
RILP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
RILP antibody, MGC154468 antibody, AI835553 antibody, Gm857 antibody, RP23-384C18.10 antibody, Rab interacting lysosomal protein antibody, Rab interacting lysosomal protein S homeolog antibody, RILP antibody, rilp.S antibody, rilp antibody, Rilp antibody
Background
RILP Antibody: The Rab interacting lysosomal protein (RILP) is lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. It is thought that RILP is a downstream effector of RAB7 and both proteins act together in the regulation of late endocytic traffic. Overexpression of RILP caused enlarged lysosomes that are more centrally located in the cell suggesting that RILP may also be involved in the regulation of lysosomal morphology. Other evidence suggests that RILP may play a role in the biogenesis of multivesicular bodies.