NKX2-6 antibody (AA 170-220)

Catalog No. ABIN6991655

Product Details anti-NKX2-6 Antibody

Target: NKX2-6 (NK2 Homeobox 6 (NKX2-6))

Binding Specificity: AA 170-220

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKX2-6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: NKX2-6 antibody is predicted to not cross-react with other NK2 homeobox family members. At least two isoforms of NKX2-6 are known to exist, this antibody will detect both isoforms

Purification: NKX2-6 Antibody is affinity chromatography purified via peptide column.

Immunogen: NKX2-6 antibody was raised against a 15 amino acid synthetic peptide near the center of human NKX2-6. The immunogen is located within amino acids 170 - 220 of NKX2-6.

Isotype: IgG

Application Details

Application Notes: NKX2-6 antibody can be used for detection of NKX2-6 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: NKX2-6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: NKX2-6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for NKX2-6

Target: NKX2-6 (NK2 Homeobox 6 (NKX2-6))

Alternative Name: NKX2-6 (NKX2-6 Products)

Synonyms: tix antibody, nkx2.6 antibody, XNkx2-10 antibody, nkx2-10-A antibody, NKX2.8 antibody, Xnkx2-10 antibody, CSX2 antibody, NKX2F antibody, NKX4-2 antibody, AV044928 antibody, Nkx-2.6 antibody, Nkx2.6 antibody, Tix antibody, tinman antibody, NK2 homeobox 6 L homeolog antibody, NK2 homeobox 6 antibody, nkx2-6.L antibody, NKX2-6 antibody, nkx2-6 antibody, Nkx2-6 antibody

Background: NKX2-6 Antibody: NKX2-6 (NK2 homeobox 6) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-6 is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are thought to be a cause for some congenital heart abnormalities.

Gene ID: 137814

NCBI Accession: NP_001129743

UniProt: A6NCS4