B9D1 antibody (C-Term)

Catalog No. ABIN6991647

Product Details anti-B9D1 Antibody

Target: B9D1 (B9 Protein Domain 1 (B9D1))

Binding Specificity: AA 130-180, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This B9D1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: At least two isoforms of B9D1 are known to exist, this antibody will only recognize the longest isoform. B9D1 antibody is predicted to not cross-react with other DNAJC family members.

Purification: B9D1 Antibody is affinity chromatography purified via peptide column.

Immunogen: B9D1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human B9D1. The immunogen is located within amino acids 130 - 180 of B9D1.

Isotype: IgG

Application Details

Application Notes: B9D1 antibody can be used for detection of B9D1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: B9D1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: B9D1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for B9D1

Target: B9D1 (B9 Protein Domain 1 (B9D1))

Alternative Name: B9D1 (B9D1 Products)

Synonyms: B9 antibody, EPPB9 antibody, MKS9 antibody, MKSR1 antibody, AW045994 antibody, Eppb9 antibody, im:6905750 antibody, im:7069491 antibody, wu:fc09g07 antibody, zgc:110733 antibody, B9 domain containing 1 antibody, B9 protein domain 1 antibody, B9D1 antibody, B9d1 antibody, b9d1 antibody

Background: B9D1 Antibody: Meckel syndrome (MKS) is an embryonic lethal, autosomal recessive disorder characterized by polycystic kidney disease, central nervous system defects, polydactyly and liver fibrosis. B9D1 is a B9 domain-containing protein, one of several that are involved in ciliogenesis. Alterations in expression of this gene have been found in a family with Meckel syndrome. B9D1, and its related protein B9D2, form a complex with MKS1, disruption of which causes MKS. B9D1 is thought to be required for normal hedgehog signaling, ciliogenesis, and ciliary protein localization.

Gene ID: 27077

NCBI Accession: NP_056496

UniProt: Q9UPM9