SPATA18 antibody (N-Term)

Catalog No. ABIN6991619

Product Details anti-SPATA18 Antibody

Target: SPATA18 (Spermatogenesis Associated 18 (SPATA18))

Binding Specificity: AA 90-140, N-Term

Reactivity: Human, Mouse, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This SPATA18 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: At least three isoforms of SPATA18 are known to exist, this antibody will detect the two longest isoforms. SPATA18 antibody is predicted to not cross-react with other SPATA family members.

Purification: SPATA18 Antibody is affinity chromatography purified via peptide column.

Immunogen: SPATA18 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human SPATA18. The immunogen is located within amino acids 90 - 140 of SPATA18.

Isotype: IgY

Application Details

Application Notes: SPATA18 antibody can be used for detection of SPATA18 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SPATA18 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SPATA18 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SPATA18

Target: SPATA18 (Spermatogenesis Associated 18 (SPATA18))

Alternative Name: SPATA18 (SPATA18 Products)

Synonyms: Mieap antibody, SPETEX1 antibody, 1700067I02Rik antibody, MIEAP antibody, spetex-1 antibody, mieap antibody, spetex1 antibody, im:7140046 antibody, zgc:110352 antibody, spermatogenesis associated 18 antibody, spermatogenesis associated 18 L homeolog antibody, SPATA18 antibody, Spata18 antibody, spata18.L antibody, spata18 antibody

Background: SPATA18 Antibody: SPATA18, also known as SPETEX-1, was initially identified as a cytoplasmic protein of elongate spermatids that is thought to be involved in differentiation process of elongate spermatids to mature spermatozoa. Recent experiments have shown that SPATA18 is a transcriptional target of p53 and p63. It has also been suggested to play a role in mitochondria quality control by inducing intramitochondrial lysosome-like organella that eliminate oxidized mitochondrial proteins.

Gene ID: 132671

NCBI Accession: NP_660306

UniProt: Q8TC71