At least three isoforms of MS4A6A are known to exist, this antibody will detect the two longer isoforms. MS4A6A antibody is predicted to not cross-react with MS4A family members.
Purification
MS4A6A Antibody is affinity chromatography purified via peptide column.
Immunogen
MS4A6A antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human MS4A6A. The immunogen is located within the first 50 amino acids of MS4A6A.
MS4A6A
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
MS4A6A antibody can be used for detection of MS4A6A by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
MS4A6A Antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C,4 °C
Storage Comment
MS4A6A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
MS4A6A
(Membrane-Spanning 4-Domains, Subfamily A, Member 6A (MS4A6A))
MS4A6A Antibody: The MS4A gene family in humans includes CD20 (MS4A1), FcRbeta (MS4A2), Htm4 (MS4A3), and at least 13 other genes encoding membrane proteins, most having characteristic tetraspanning topology and similar intron/exon splice boundaries. All family members display unique expression patterns among hematopoietic cells and non-lymphoid tissues. The function of MS4A6A has been suggested to be involved in signal transduction as a component of a multimeric receptor complex in Alzheimer's disease and cancer.