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AFAP1L1 antibody (N-Term)

AFAP1L1 Reactivity: Mouse, Human WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991605
  • Target See all AFAP1L1 Antibodies
    AFAP1L1 (Actin Filament Associated Protein 1-Like 1 (AFAP1L1))
    Binding Specificity
    • 12
    • 7
    • 2
    AA 70-120, N-Term
    Reactivity
    • 15
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse, Human
    Host
    • 16
    Rabbit
    Clonality
    • 16
    Polyclonal
    Conjugate
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    This AFAP1L1 antibody is un-conjugated
    Application
    • 16
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    At least four isoforms of AFAP1L1 are known to exist. This antibody is predicted to not cross-react with other AFAP family members.
    Purification
    AFAP1L Antibody is affinity chromatography purified via peptide column.
    Immunogen
    AFAP1L1 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human AFAP1L1. The immunogen is located within amino acids 70 - 120 of AFAP1L.
    Isotype
    IgG
    Top Product
    Discover our top product AFAP1L1 Primary Antibody
  • Application Notes
    AFAP1L1 antibody can be used for detection of AFAP1L1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    AFAP1L Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    AFAP1L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    AFAP1L1 (Actin Filament Associated Protein 1-Like 1 (AFAP1L1))
    Alternative Name
    AFAP1L (AFAP1L1 Products)
    Synonyms
    AI173486 antibody, RGD1311580 antibody, afap1l1 antibody, zgc:114084 antibody, sb:cb932 antibody, zgc:153096 antibody, actin filament associated protein 1-like 1 antibody, actin filament associated protein 1 like 1 antibody, actin filament associated protein 1-like 1a antibody, actin filament associated protein 1-like 1b antibody, Afap1l1 antibody, AFAP1L1 antibody, afap1l1a antibody, afap1l1b antibody
    Background
    AFAP1L Antibody: The actin filament-associated protein 1 (AFAP1)-like 1 protein is one of three members in the AFAP1 family of adaptor proteins. Like AFAP1, AFAP1L1 is an actin binding protein that has a role in actin cytoskeleton arrangement, but AFAP1L1 is thought to have a unique function distinct from AFAP1. AFAP1L1 colocalizes with cortactin and localizes to invadosomes, highly dynamic, actin-rich adhesion structures harboring metalloproteases, suggesting that AFAP1L1 affects invadosome formation (1, 4). Recent reports suggest that AFAP1L1 can be used as a prognostic marker for spindle cell sarcomas.
    Gene ID
    134265
    NCBI Accession
    NP_689619
    UniProt
    Q8TED9
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