Coronin 7 antibody (C-Term)

Catalog No. ABIN6991571

Product Details anti-Coronin 7 Antibody

Target: Coronin 7 (CORO7)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Coronin 7 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: Multiple isoforms of Coronin 7 are known to exist

Purification: Coronin 7 Antibody is affinity chromatography purified via peptide column.

Immunogen: Coronin 7 antibody was raised against an 17 amino acid synthetic peptide near the carboxy terminus of human Coronin 7. The immunogen is located within the last 50 amino acids of Coronin 7.

Isotype: IgG

Application Details

Application Notes: Coronin 7 antibody can be used for detection of Coronin 7 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Coronin 7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Coronin 7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Coronin 7

Target: Coronin 7 (CORO7)

Alternative Name: Coronin 7 (CORO7 Products)

Synonyms: coronin-7 antibody, zgc:112352 antibody, MGC99303 antibody, Coronin-7 antibody, DKFZp459E084 antibody, 0610011B16Rik antibody, CRN7 antibody, POD1 antibody, AW048373 antibody, AW556392 antibody, Crn7 antibody, coronin 7 antibody, coronin 7 S homeolog antibody, coronin-7 antibody, CORO7 antibody, coro7 antibody, coro7.S antibody, LOC100477739 antibody, Coro7 antibody

Background: Coronin 7 Antibody: Coronins, such as Coronin 7, constitute an evolutionarily conserved family of WD-repeat actin-binding proteins whose function is thought to be regulating the cytoskeleton. Unlike other cytoplasmically localized Coronins, Coronin 7 localizes in part to the Golgi complex and is thought to play a role in Golgi complex morphology and function. Other experiments indicate that Coronin 7 interacts with the anti-proliferative protein TOB1 and enhances its degradation though the SCF ubiquitin ligase (E3) complex.

Gene ID: 79585

NCBI Accession: NP_078811

UniProt: P57737