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CHD7 antibody (N-Term)

CHD7 Reactivity: Human, Mouse WB, ELISA, IHC (p), IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991566
  • Target See all CHD7 Antibodies
    CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))
    Binding Specificity
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 670-720, N-Term
    Reactivity
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 7
    • 1
    • 1
    Rabbit
    Clonality
    • 9
    Polyclonal
    Conjugate
    • 9
    This CHD7 antibody is un-conjugated
    Application
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Specificity
    Multiple isoforms of CHD7 are known to exist.
    Purification
    CHD7 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    CHD7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CHD7. The immunogen is located within amino acids 670 - 720 of CHD7.
    Isotype
    IgG
    Top Product
    Discover our top product CHD7 Primary Antibody
  • Application Notes
    CHD7 antibody can be used for detection of CHD7 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    CHD7 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    CHD7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))
    Alternative Name
    CHD7 (CHD7 Products)
    Synonyms
    CHD7 antibody, fd19h06 antibody, si:ch211-197o6.2 antibody, wu:cegs2051 antibody, wu:fb37f10 antibody, wu:fb39h04 antibody, wu:fd19h06 antibody, HH5 antibody, IS3 antibody, KAL5 antibody, A730019I05Rik antibody, Cycn antibody, Cyn antibody, Dz antibody, Edy antibody, Flo antibody, GENA 47 antibody, GENA 60 antibody, Gena 52 antibody, Lda antibody, Mt antibody, Obt antibody, Todo antibody, WBE1 antibody, Whi antibody, metis antibody, chromodomain helicase DNA binding protein 7 L homeolog antibody, chromodomain helicase DNA binding protein 7 antibody, chd7.L antibody, CHD7 antibody, chd7 antibody, Chd7 antibody
    Background
    CHD7 Antibody: CHD proteins belong to a superfamily of proteins of ATP-dependent chromatin remodeling enzymes that have a unique combination of functional domains, including two N-terminal chromodomains, a SNF2-like ATPase/helicase domain and a DNA-binding domain. These proteins are thought to play a role in early embryonic development by affecting chromatin structure and gene expression. Mutations in one member of this family, CHD7, result in CHARGE syndrome. It colocalizes with embryonic stem (ES) cell master regulators OCT4/POU5F1, SOX2, and NANOG and is thought to modulate ES-specific gene transcription. Together with SOX2, CHD7 has been suggested to also regulate several human disease genes.
    Gene ID
    55636
    UniProt
    Q9P2D1
    Pathways
    Sensory Perception of Sound, Chromatin Binding
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