KCNK13 antibody is predicted to not cross-react with other KCNK protein family members.
Purification
KCNK13 Antibody is affinity chromatography purified via peptide column.
Immunogen
KCNK13 antibody was raised against a 15 amino acid synthetic peptide near the center of human KCNK13. The immunogen is located within amino acids 150 - 200 of KCNK13.
KCNK13
Reactivity: Human
Host: Rabbit
Polyclonal
FITC
Application Notes
KCNK13 antibody can be used for detection of KCNK13 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
KCNK13 Antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C,4 °C
Storage Comment
KCNK13 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
KCNK13
(Potassium Channel Subfamily K Member 13 (KCNK13))
BB085247 antibody, F730021E22Rik antibody, Gm1570 antibody, Gm1685 antibody, K2p13.1 antibody, THIK-1 antibody, THIK1 antibody, prdx1 antibody, kcnk13 antibody, si:ch211-173b9.3 antibody, zgc:171694 antibody, potassium channel, subfamily K, member 13 antibody, potassium two pore domain channel subfamily K member 13 antibody, potassium channel subfamily K member 13 antibody, potassium channel, subfamily K, member 13b antibody, potassium channel, subfamily K, member 13a antibody, Kcnk13 antibody, KCNK13 antibody, Tsp_07890 antibody, kcnk13b antibody, kcnk13a antibody
Background
KCNK13 Antibody: The closely related proteins KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK13 is expressed mainly in the brain, but is also observed in kidneys. KCNK13 has been suggested to be a candidate for the Cs+-permeable K+ channel activated by GABA(B) receptors.