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TMEM88 antibody (C-Term)

TMEM88 Reactivity: Human, Mouse, Rat ELISA, WB, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991552
  • Target See all TMEM88 products
    TMEM88 (Transmembrane Protein 88 (TMEM88))
    Binding Specificity
    AA 110-160, C-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 5
    Rabbit
    Clonality
    • 5
    Polyclonal
    Conjugate
    • 2
    • 1
    • 1
    • 1
    This TMEM88 antibody is un-conjugated
    Application
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    At least two isoforms of TMEM88 are known to exist, this antibody will recognize both isoforms.
    Purification
    TMEM88 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    TMEM88 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human TMEM88. The immunogen is located within amino acids 110 - 160 of TMEM88.
    Isotype
    IgG
  • Application Notes
    TMEM88 antibody can be used for detection of TMEM88 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    TMEM88 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    TMEM88 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    TMEM88 (Transmembrane Protein 88 (TMEM88))
    Alternative Name
    TMEM88 (TMEM88 Products)
    Synonyms
    2600017H02Rik antibody, RGD1561781 antibody, zgc:77242 antibody, transmembrane protein 88 antibody, transmembrane protein 88B antibody, transmembrane protein 88 a antibody, Tmem88 antibody, TMEM88 antibody, TMEM88B antibody, tmem88 antibody, tmem88a antibody
    Background
    TMEM88 Antibody: Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.
    Gene ID
    92162
    UniProt
    Q6PEY1
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