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ZNF219 antibody (N-Term)

ZNF219 Reactivity: Human, Rat, Mouse WB, ELISA, IHC (p), IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991505
  • Target See all ZNF219 Antibodies
    ZNF219 (Zinc Finger Protein 219 (ZNF219))
    Binding Specificity
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 90-140, N-Term
    Reactivity
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 10
    Rabbit
    Clonality
    • 10
    Polyclonal
    Conjugate
    • 10
    This ZNF219 antibody is un-conjugated
    Application
    • 10
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Specificity
    At least two isoforms of ZFP219 are known to exist, this antibody will recognize both.
    Purification
    ZFP219 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    ZFP219 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ZFP219. The immunogen is located within amino acids 90 - 140 of ZFP219.
    Isotype
    IgG
    Top Product
    Discover our top product ZNF219 Primary Antibody
  • Application Notes
    ZFP219 antibody can be used for detection of ZFP219 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    ZFP219 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    ZFP219 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    ZNF219 (Zinc Finger Protein 219 (ZNF219))
    Alternative Name
    ZFP219 (ZNF219 Products)
    Synonyms
    ZNF219 antibody, ZFP219 antibody, Znf219 antibody, 2010302A17Rik antibody, zinc finger protein 219 antibody, ZNF219 antibody, Zfp219 antibody
    Background
    ZFP219 Antibody: ZFP219 is a developmentally regulated member of the Kruppel-like zinc finger gene family that is thought to function as a transcriptional repressor. Yeast two-hybrid screening showed association with Sox9, a transcription factor that is essential for chondrogenesis. ZFP219 is specifically expressed in the developing limb buds and colocalizes with Sox9 in the nucleus. Knockdown of ZFP219 expression decreased Sox9-induced mRNA expression, and a dominant-negative mutant of ZFP219 inhibited Bmp2-induced chondrocyte differentiation, suggesting that ZFP219 plays an important role as a transcriptional partner of Sox9 in the regulation of chondrocyte differentiation.
    Molecular Weight
    Predicted: 80 kDa

    Observed: 78 kDa
    Gene ID
    51222
    NCBI Accession
    NP_001095142
    UniProt
    Q9P2Y4
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