NKX3-2 antibody (AA 180-230)

Catalog No. ABIN6991495

Product Details anti-NKX3-2 Antibody

Target: NKX3-2 (NK3 Homeobox 2 (NKX3-2))

Binding Specificity: AA 180-230

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKX3-2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: BAPX1 antibody is predicted not to cross-react with other NKX homeobox proteins.

Purification: BAPX1 Antibody is affinity chromatography purified via peptide column.

Immunogen: BAPX1 antibody was raised against a 19 amino acid synthetic peptide near the center of human BAPX1. The immunogen is located within amino acids 180 - 230 of BAPX1.

Isotype: IgG

Application Details

Application Notes: BAPX1 antibody can be used for detection of BAPX1 by Western blot at 1 and 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: BAPX1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: BAPX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for NKX3-2

Target: NKX3-2 (NK3 Homeobox 2 (NKX3-2))

Alternative Name: BAPX1 (NKX3-2 Products)

Synonyms: bapx1 antibody, Xbap antibody, bapx1-A antibody, nkx3.2 antibody, BAPX1 antibody, NKX-3.2 antibody, NKX3.2 antibody, NKX3B antibody, SMMD antibody, Bapx1 antibody, Nkx-3.2 antibody, NK3 homeobox 2 antibody, NK3 homeobox 2 S homeolog antibody, NKX3-2 antibody, nkx3.2 antibody, nkx3-2.S antibody, Nkx3-2 antibody

Background: BAPX1 Antibody: BAPX1 is the mammalian homolog of the Drosophila bagpipe homeobox gene and is expressed in the splanchnic mesoderm and embryonic skeleton. It is one of the earliest developmental markers for the sclerotome portion of the somite and the gut mesentery. BAPX1 is required for normal skeletal development, homozygous inactivating mutations in the BAPX1 gene result in spodylo-megaepiphyseal-metaphyseal dysplasia (SMMD). It has also been suggested to play a role in the proper development of the mammalian gut and is required for distal stomach development as part of a BARX1-dependent pathway.

Gene ID: 579

NCBI Accession: NP_001180

UniProt: P78367