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N4BP1 antibody (N-Term)

N4BP1 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991485
  • Target See all N4BP1 Antibodies
    N4BP1 (NEDD4 Binding Protein 1 (N4BP1))
    Binding Specificity
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 14
    • 1
    Rabbit
    Clonality
    • 15
    Polyclonal
    Conjugate
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This N4BP1 antibody is un-conjugated
    Application
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    At least three isoforms of N4BP1 are known to exist, this antibody will only detect the longest isoform.
    Purification
    N4BP1 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    N4BP1 antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of human N4BP1. The immunogen is located within the first 50 amino acids of N4BP1.
    Isotype
    IgG
    Top Product
    Discover our top product N4BP1 Primary Antibody
  • Application Notes
    N4BP1 antibody can be used for detection of N4BP1 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    N4BP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    N4BP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    N4BP1 (NEDD4 Binding Protein 1 (N4BP1))
    Alternative Name
    N4BP1 (N4BP1 Products)
    Synonyms
    AI481586 antibody, C81621 antibody, RGD1305179 antibody, wu:fi03b05 antibody, zgc:66437 antibody, NEDD4 binding protein 1 antibody, Nedd4 binding protein 1 antibody, nedd4 binding protein 1 antibody, nedd4 binding protein 1 L homeolog antibody, N4BP1 antibody, N4bp1 antibody, n4bp1 antibody, n4bp1.L antibody
    Background
    N4BP1 Antibody: Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.
    Gene ID
    9683
    NCBI Accession
    NP_694574
    UniProt
    O75113
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