ZBTB7A antibody (N-Term)

Catalog No. ABIN6991471

Product Details anti-ZBTB7A Antibody

Target: ZBTB7A (Zinc Finger and BTB Domain Containing 7A (ZBTB7A))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB7A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: At least two isoforms of ZBTB7A are known to exist, this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other ZBTB protein family members.

Purification: ZBTB7A Antibody is affinity chromatography purified via peptide column.

Immunogen: ZBTB7A antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human ZBTB7A. The immunogen is located within the first 50 amino acids of ZBTB7A.

Isotype: IgG

Application Details

Application Notes: ZBTB7A antibody can be used for detection of ZBTB7A by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZBTB7A Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: ZBTB7A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ZBTB7A

Target: ZBTB7A (Zinc Finger and BTB Domain Containing 7A (ZBTB7A))

Alternative Name: ZBTB7A (ZBTB7A Products)

Synonyms: ZBTB7A antibody, FBI-1 antibody, FBI1 antibody, LRF antibody, ZBTB7 antibody, ZNF857A antibody, pokemon antibody, 9030619K07Rik antibody, 9130006G12Rik antibody, AI452336 antibody, Lrf antibody, Pokemon antibody, Zbtb7 antibody, OCZF antibody, zinc finger and BTB domain containing 7A antibody, zinc finger and BTB domain containing 7C antibody, zinc finger and BTB domain containing 7a antibody, ZBTB7A antibody, ZBTB7C antibody, Zbtb7a antibody

Background: ZBTB7A Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB7A, also known as LRF, was initially identified as a potential target of the LAZ-3/BCL-6 oncogene. Later reports demonstrated that it could bind to the wild-type IST (inducer of short transcripts) elements of HIV-1 long terminal repeats (LTRs) and stimulate Tat activity on the HIV-1 LTR. More recently it ZBTB7A has been recognized as a proto-oncogene whose overexpression contributes to malignancy in breast cancer and functions as a co-repressor of the androgen receptor in prostate cancer cells.

Gene ID: 51341

UniProt: O95365