PIWIL3 antibody (N-Term)

Catalog No. ABIN6991436

Product Details anti-PIWIL3 Antibody

Target: PIWIL3 (Piwi-Like 3 (PIWIL3))

Binding Specificity: AA 130-180, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIWIL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purification: PIWI-L3 Antibody is affinity chromatography purified via peptide column.

Immunogen: PIWI-L3 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human PIWI-L3. The immunogen is located within amino acids 130 - 180 of PIWI-L3.

Isotype: IgG

Application Details

Application Notes: PIWI-L3 antibody can be used for detection of PIWI-L3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PIWI-L3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: PIWI-L3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PIWIL3

Target: PIWIL3 (Piwi-Like 3 (PIWIL3))

Alternative Name: PIWI-L3 (PIWIL3 Products)

Synonyms: HIWI3 antibody, piwi like RNA-mediated gene silencing 3 antibody, piwi-like protein 1 antibody, piwi-like 3 (Drosophila) antibody, PIWIL3 antibody, LOC486307 antibody

Background: PIWI-L3 Antibody: PIWI-L3 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. Recent studies have shown that overexpression of PIWI-L3 (as well as other PIWI-like proteins) are potential biomarkers for astrocytic glioma, meningioma, and other cancers.

Gene ID: 440822

NCBI Accession: NP_001008496

UniProt: Q7Z3Z3