NLRP11 antibody (C-Term)

Catalog No. ABIN6991407

Product Details anti-NLRP11 Antibody

Target: NLRP11 (NLR Family, Pyrin Domain Containing 11 (NLRP11))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Purification: NALP11 Antibody is affinity chromatography purified via peptide column.

Immunogen: NALP11 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human NALP11. The immunogen is located within the last 50 amino acids of NALP11.

Isotype: IgG

Application Details

Application Notes: NALP11 antibody can be used for detection of NALP11 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: NALP11 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: NALP11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for NLRP11

Target: NLRP11 (NLR Family, Pyrin Domain Containing 11 (NLRP11))

Alternative Name: NALP11 (NLRP11 Products)

Synonyms: CLR19.6 antibody, NALP11 antibody, NOD17 antibody, PAN10 antibody, PYPAF6 antibody, PYPAF7 antibody, NLR family pyrin domain containing 11 antibody, NLRP11 antibody

Background: NALP11 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP11 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP11, it has been suggested that it has been associated with Crohn's disease.

Gene ID: 204801

NCBI Accession: NP_659444

UniProt: P59045

Pathways: Inflammasome