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SCUBE1 antibody (AA 460-510)

SCUBE1 Reactivity: Human ELISA, WB, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991373
  • Target See all SCUBE1 Antibodies
    SCUBE1 (Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1))
    Binding Specificity
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 460-510
    Reactivity
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 12
    Rabbit
    Clonality
    • 12
    Polyclonal
    Conjugate
    • 9
    • 1
    • 1
    • 1
    This SCUBE1 antibody is un-conjugated
    Application
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Purification
    SCUBE1 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    SCUBE1 antibody was raised against a 14 amino acid synthetic peptide near the center of human SCUBE1. The immunogen is located within amino acids 460 - 510 of SCUBE1.
    Isotype
    IgG
    Top Product
    Discover our top product SCUBE1 Primary Antibody
  • Application Notes
    SCUBE1 antibody can be used for detection of SCUBE1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    SCUBE1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    SCUBE1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SCUBE1 (Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1))
    Alternative Name
    SCUBE1 (SCUBE1 Products)
    Synonyms
    7330410C13Rik antibody, A630023E24Rik antibody, signal peptide, CUB domain and EGF like domain containing 1 antibody, signal peptide, CUB domain, EGF-like 1 antibody, SCUBE1 antibody, Scube1 antibody
    Background
    SCUBE1 Antibody: SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity, genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.
    Gene ID
    80274
    NCBI Accession
    NP_766638
    UniProt
    Q8IWY4
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