ELOVL7 antibody (N-Term)

Catalog No. ABIN6991291

Product Details anti-ELOVL7 Antibody

Target: ELOVL7 (ELOVL Fatty Acid Elongase 7 (ELOVL7))

Binding Specificity: AA 40-90, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELOVL7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: ELOVL7 Antibody is affinity chromatography purified via peptide column.

Immunogen: ELOVL7 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ELOVL7. The immunogen is located within amino acids 40 - 90 of ELOVL7.

Isotype: IgG

Application Details

Application Notes: ELOVL7 antibody can be used for detection of ELOVL7 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: ELOVL7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: ELOVL7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ELOVL7

Target: ELOVL7 (ELOVL Fatty Acid Elongase 7 (ELOVL7))

Alternative Name: ELOVL7 (ELOVL7 Products)

Background: ELOVL7 Antibody: Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0-) and has been suggested to be involved in prostate cancer growth through saturated long-chain fatty acid metabolism. The metabolic pathways of long-chain fatty acids play an important role in the maintenance of membrane lipid composition and the generation of cell signaling precursor molecules such as eicosanoids and sphingosine-1 phosphate. Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes, its expression is regulated by the microRNA miR-219.

Gene ID: 79993

NCBI Accession: NP_001098028

UniProt: A1L3X0