SLFN12 antibody (C-Term)

Catalog No. ABIN6991244

Product Details anti-SLFN12 Antibody

Target: SLFN12 (Schlafen Family Member 12 (SLFN12))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLFN12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: SLFN12 Antibody is affinity chromatography purified via peptide column.

Immunogen: SLFN12 antibody was raised against a 12 amino acid synthetic peptide from near the carboxy terminus human SLFN12. The immunogen is located within the last 50 amino acids of SLFN12.

Isotype: IgG

Application Details

Application Notes: SLFN12 antibody can be used for detection of SLFN12 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SLFN12 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SLFN12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SLFN12

Target: SLFN12 (Schlafen Family Member 12 (SLFN12))

Alternative Name: SLFN12 (SLFN12 Products)

Synonyms: SLFN3 antibody, SLFN12L antibody, schlafen family member 12 antibody, SLFN12 antibody

Background: SLFN12 Antibody: Despite being first described several years ago, the roles of the Schlafen (SLFN) family of proteins remain largely unknown. The SLFN genes are preferentially expressed in lymphoid tissues and differentially regulated during thymocyte maturation. It is thought that many play roles in cell growth, hemopoietic cell differentiation, and T cell development and maturation. Most members contain at least one divergent AAA domain (AAA_4) that may play a role in ATP binding. Although also known as SLFN3, a Schlafen family member that may be a marker of T cell activation, human SLFN12 has relatively low homology to SLFN3 in other species. Loss of the SLFN12 gene due to deletion is associated with Kabuki syndrome, a multiple congenital anomaly syndrome, suggesting SLFN may play a role in this genetic condition.

Gene ID: 55106

NCBI Accession: NP_060512

UniProt: Q8IYM2