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ZNF536 antibody (N-Term)

ZNF536 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991232
  • Target See all ZNF536 Antibodies
    ZNF536 (Zinc Finger Protein 536 (ZNF536))
    Binding Specificity
    • 8
    • 8
    • 6
    AA 30-80, N-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 15
    Rabbit
    Clonality
    • 15
    Polyclonal
    Conjugate
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    This ZNF536 antibody is un-conjugated
    Application
    • 15
    • 13
    • 13
    • 12
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Purification
    ZNF536 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    ZNF536 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human ZNF536. The immunogen is located within amino acids 30 - 80 of ZNF536.
    Isotype
    IgG
    Top Product
    Discover our top product ZNF536 Primary Antibody
  • Application Notes
    ZNF536 antibody can be used for detection of ZNF536 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    ZNF536 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    ZNF536 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    ZNF536 (Zinc Finger Protein 536 (ZNF536))
    Alternative Name
    ZNF536 (ZNF536 Products)
    Synonyms
    9630010P11Rik antibody, Znf536 antibody, mKIAA0390 antibody, RGD1563363 antibody, zinc finger protein 536 antibody, ZNF536 antibody, Zfp536 antibody
    Background
    ZNF536 Antibody: ZNF536 is a recently identified zinc-finger protein that is expressed primarily in the developing nervous system and the cerebral cortex, hippocampus, and hypothalamus. ZNF536 possess ten zinc fingers and interacts with CtBP1, a corepressor for gene transcription. It is most closely related to transcriptional repressor ZNF219. Overexpression of ZNF536 in embryonic stem cells dramatically reduced the mRNA levels of neuronal marker genes such as Pax6, MAP2, and beta-tubulin III following retinoic acid (RA)-induced differentiation, while depletion of ZNF536 via RNAi resulted in elevated mRNA levels of these genes, indicating its role in inhibiting neuronal cell differentiation. Overexpression of RA receptor a rescues the inhibitory role of ZNF536, suggesting that ZNF536 might inhibit RA response element-mediated transcriptional activity.
    Gene ID
    9745
    NCBI Accession
    NP_055532
    UniProt
    O15090
    Pathways
    Retinoic Acid Receptor Signaling Pathway
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