MARVELD1 antibody (N-Term)

Catalog No. ABIN6991231

Product Details anti-MARVELD1 Antibody

Target: MARVELD1 (MARVEL Domain Containing 1 (MARVELD1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARVELD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: MARVELD1 Antibody is affinity chromatography purified via peptide column.

Immunogen: MARVELD1 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human MARVELD1. The immunogen is located within the first 50 amino acids of MARVELD1.

Isotype: IgG

Application Details

Application Notes: MARVELD1 antibody can be used for detection of MARVELD1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: MARVELD1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: MARVELD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for MARVELD1

Target: MARVELD1 (MARVEL Domain Containing 1 (MARVELD1))

Alternative Name: MARVELD1 (MARVELD1 Products)

Synonyms: Mrvldc1 antibody, AI504298 antibody, GB14 antibody, MARVD1 antibody, MRVLDC1 antibody, RP11-548K23.8 antibody, bA548K23.8 antibody, MARVEL domain containing 1 antibody, MARVEL (membrane-associating) domain containing 1 antibody, Marveld1 antibody, MARVELD1 antibody

Background: MARVELD1 Antibody: MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.

Gene ID: 83742

UniProt: Q9BSK0