INSM2 antibody (C-Term)

Catalog No. ABIN6991198

Product Details anti-INSM2 Antibody

Target: INSM2 (Insulinoma-Associated 2 (INSM2))

Binding Specificity: AA 340-390, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INSM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: IA-6 Antibody is affinity chromatography purified via peptide column.

Immunogen: IA-6 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human IA-6. The immunogen is located within amino acids 340 - 390 of IA-6.

Isotype: IgG

Application Details

Application Notes: IA-6 antibody can be used for detection of IA-6 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: IA-6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: IA-6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for INSM2

Target: INSM2 (Insulinoma-Associated 2 (INSM2))

Alternative Name: IA-6 (INSM2 Products)

Synonyms: INSM2 antibody, IA-6 antibody, IA6 antibody, mlt1 antibody, Mlt1 antibody, INSM transcriptional repressor 2 antibody, insulinoma-associated 2 antibody, INSM2 antibody, Insm2 antibody

Background: IA-6 Antibody: IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription.

Gene ID: 84684

UniProt: Q96T92