Hemagglutinin antibody (AA 180-230)

Catalog No. ABIN6991142

Product Details anti-Hemagglutinin Antibody

Target: Hemagglutinin (HA)

Binding Specificity: AA 180-230

Reactivity: Influenza A Virus H1N1

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hemagglutinin antibody is un-conjugated

Application: ELISA

Specificity: This antibody is specific for the seasonal H1N1 influenza Hemagglutinin and will not recognize the corresponding Hemagglutinin sequence from the swine-origin H1N1 influenza (A/California/14/2009 (H1N1)). Will not cross-react with peptide corresponding to the swine-origin H1N1 influenza Hemagglutinin.

Purification: Seasonal H1N1 Hemagglutinin Antibody is affinity chromatography purified via peptide column.

Immunogen: Hemagglutinin antibody was raised against a synthetic peptide from the Hemagglutinin protein. The peptide sequence is unique from the peptide sequence for product ABIN6991140 and 5239. This antibody is a cognate pair with antibody ABIN6991143. The immunogen is located within amino acids 180 - 230 of Seasonal H1N1 Hemagglutinin.

Isotype: IgG

Application Details

Application Notes: Hemagglutinin antibody can be used for the detection of the Hemagglutinin protein from the H1N1 strain of common influenza A in ELISA. It will detect 2 ng of free peptide at 1 μ,g/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Seasonal H1N1 Hemagglutinin Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Seasonal H1N1 Hemagglutinin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Hemagglutinin

Target: Hemagglutinin (HA)

Alternative Name: Seasonal H1N1 Hemagglutinin (HA Products)

Synonyms: hemagglutinin antibody, Hemagglutinin antibody, HA antibody, HA antibody, ha antibody

Target Type: Influenza Protein

Background: Seasonal H1N1 Hemagglutinin Antibody: Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and the United States. The virus spread quickly around the world and on June 11, 2009, the World Health Organization declared it a pandemic. Influenza A virus has one of sixteen possible Hemagglutinin (HA) surface proteins and one of nine possible Neuraminidase (NA) surface proteins. The Hemagglutinin protein facilitates viral attachment while Neuraminidase is involved in viral release. These proteins also elicit immune responses that prevent infection or independently reduce viral replication. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin. The distinct antigenic properties of the new swine virus compared with seasonal influenza A (H1N1) virus suggest that human immunity against new swine influenza virus is limited, although the age distribution of reported cases suggests some degree of protection in older age groups.

UniProt: B0VX44