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ST3GAL6 antibody (C-Term)

ST3GAL6 Reactivity: Human, Mouse, Rat WB, ELISA, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991119
  • Target See all ST3GAL6 Antibodies
    ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))
    Binding Specificity
    AA 230-280, C-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 1
    Rabbit
    Clonality
    • 1
    Polyclonal
    Conjugate
    • 1
    This ST3GAL6 antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    Purification
    ST3gal6 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    ST3gal6 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human ST3gal6. The immunogen is located within amino acids 230 - 280 of ST3gal6.
    Isotype
    IgG
    Top Product
    Discover our top product ST3GAL6 Primary Antibody
  • Application Notes
    ST3gal6 antibody can be used for detection of ST3gal6 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    ST3gal6 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    ST3gal6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))
    Alternative Name
    ST3gal6 (ST3GAL6 Products)
    Synonyms
    SIAT10 antibody, ST3GALVI antibody, 1700023B24Rik antibody, AI930218 antibody, AW552396 antibody, Siat10 antibody, St3galVI antibody, ST3GAL-VI antibody, ST3 beta-galactoside alpha-2,3-sialyltransferase 6 antibody, ST3GAL6 antibody, St3gal6 antibody
    Background
    ST3gal6 Antibody: Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.
    Gene ID
    10402
    NCBI Accession
    NP_006091
    UniProt
    Q9Y274
    Pathways
    Glycosaminoglycan Metabolic Process
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