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RCAN2 antibody (AA 70-120)

RCAN2 Reactivity: Human, Mouse, Rat ELISA, WB, IHC (p), IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991070
  • Target See all RCAN2 Antibodies
    RCAN2 (Regulator of Calcineurin 2 (RCAN2))
    Binding Specificity
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 70-120
    Reactivity
    • 28
    • 19
    • 12
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 26
    • 2
    Rabbit
    Clonality
    • 28
    Polyclonal
    Conjugate
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RCAN2 antibody is un-conjugated
    Application
    • 16
    • 12
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Purification
    RCAN2 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    RCAN2 antibody was raised against a 14 amino acid synthetic peptide near the center of human RCAN2. The immunogen is located within amino acids 70 - 120 of RCAN2.
    Isotype
    IgG
    Top Product
    Discover our top product RCAN2 Primary Antibody
  • Application Notes
    RCAN2 antibody can be used for detection of RCAN2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    RCAN2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    RCAN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    RCAN2 (Regulator of Calcineurin 2 (RCAN2))
    Alternative Name
    RCAN2 (RCAN2 Products)
    Synonyms
    DSCR1L1 antibody, si:ch211-124g24.1 antibody, zgc:85746 antibody, RCAN2 antibody, DKFZp459H071 antibody, rcan2 antibody, CSP2 antibody, MCIP2 antibody, RCN2 antibody, ZAKI-4 antibody, ZAKI4 antibody, Csp2 antibody, Dscr1l1 antibody, Dcip2 antibody, Zaki-4 antibody, regulator of calcineurin 2 antibody, rcan2 antibody, RCAN2 antibody, Rcan2 antibody
    Background
    RCAN2 Antibody: Regulator of calcineurin 2 (RCAN2), also known as ZAKI4 and DSCR1L1, is expressed as two isoforms differing at their N-terminus. The longer of the two (isoform 1) is expressed exclusively in the brain, while isoform 2 is ubiquitously expressed, with highest expression in brain, heart, and muscle. Both isoforms bind to the catalytic subunit of calcineurin, a Ca++-dependent protein phosphatase involved in several neuronal functions, though their C-terminal region and inhibit calcineurin's activity. Unlike isoform 1 of RCAN2, the expression of the second isoform is not induced by the thyroid hormone T3. RCAN2 is a member of a family of three endogenous calcineurin regulators that are located near the minimal supernumerary fragment of chromosome 21 in individuals with Down syndrome, suggesting that they play a role in this syndrome. Multiple isoforms of RCAN2 are known to exist.
    Gene ID
    53901
    UniProt
    Q9JHG2
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