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FNIP2 antibody (C-Term)

FNIP2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991067
  • Target See all FNIP2 Antibodies
    FNIP2 (Folliculin Interacting Protein 2 (FNIP2))
    Binding Specificity
    • 9
    • 8
    • 7
    • 3
    • 1
    AA 860-910, C-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 19
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    This FNIP2 antibody is un-conjugated
    Application
    • 19
    • 14
    • 14
    • 14
    • 4
    • 3
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.
    Purification
    FNIP2 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    FNIP2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human FNIP2. The immunogen is located within amino acids 860 - 910 of FNIP2.
    Isotype
    IgG
    Top Product
    Discover our top product FNIP2 Primary Antibody
  • Application Notes
    FNIP2 antibody can be used for detection of FNIP2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

    Antibody validated: Western Blot in rat samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    FNIP2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    FNIP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    FNIP2 (Folliculin Interacting Protein 2 (FNIP2))
    Alternative Name
    FNIP2 (FNIP2 Products)
    Synonyms
    LOC797213 antibody, FNIPL antibody, MAPO1 antibody, D630023B12Rik antibody, mKIAA1450 antibody, RGD1562174 antibody, folliculin interacting protein 2 antibody, si:ch211-42i9.8 antibody, FNIP2 antibody, si:ch211-42i9.8 antibody, fnip2 antibody, Fnip2 antibody
    Background
    FNIP2 Antibody: FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, a protein that shares 49 % identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation. FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship.
    Gene ID
    57600
    NCBI Accession
    NP_065891
    UniProt
    Q9P278
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