METTL7A antibody (C-Term)

Catalog No. ABIN6991008

Product Details anti-METTL7A Antibody

Target: METTL7A (Methyltransferase Like 7A (METTL7A))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL7A antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: At least two isoforms of MettL7A are known to exist. This MettL7A antibody is predicted to not cross-react with MettL7B.

Purification: MettL7A Antibody is affinity chromatography purified via peptide column.

Immunogen: MettL7A antibody was raised against a 12 amino acid synthetic peptide near the carboxy terminus of human MettL7A. The immunogen is located within the last 50 amino acids of MettL7A.

Isotype: IgG

Application Details

Application Notes: MettL7A antibody can be used for detection of MettL7A by Western blot at 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: MettL7A Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: MettL7A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for METTL7A

Target: METTL7A (Methyltransferase Like 7A (METTL7A))

Alternative Name: MettL7A (METTL7A Products)

Synonyms: AAM-B antibody, 2210414H16Rik antibody, 3300001H21Rik antibody, Aam-B antibody, Mettl7a antibody, UbiE1 antibody, RGD1308407 antibody, MGC82719 antibody, zgc:153889 antibody, MGC145311 antibody, DKFZp459L026 antibody, methyltransferase like 7A antibody, methyltransferase like 7A1 antibody, methyltransferase like 7A L homeolog antibody, METTL7A antibody, Mettl7a1 antibody, Mettl7a antibody, mettl7a.L antibody, mettl7a antibody

Background: MettL7A Antibody: MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.

Gene ID: 25840

NCBI Accession: NP_054752

UniProt: Q9H8H3