PLXDC1 antibody (C-Term)

Catalog No. ABIN6990799

Product Details anti-PLXDC1 Antibody

Target: PLXDC1 (Plexin Domain Containing 1 (PLXDC1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLXDC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: TEM7 Antibody is affinity chromatography purified via peptide column.

Immunogen: TEM7 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human TEM7. The immunogen is located within the last 50 amino acids of TEM7.

Isotype: IgG

Application Details

Application Notes: TEM7 antibody can be used for detection of TEM7 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TEM7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TEM7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PLXDC1

Target: PLXDC1 (Plexin Domain Containing 1 (PLXDC1))

Alternative Name: TEM7 (PLXDC1 Products)

Synonyms: PLXDC1 antibody, TEM3 antibody, TEM7 antibody, 2410003I07Rik antibody, AI848450 antibody, Tem7 antibody, Arl12 antibody, plexin domain containing 1 antibody, PLXDC1 antibody, Plxdc1 antibody

Background: TEM7 Antibody: Tumor endothelial marker 7 (TEM7) was identified through serial analysis of gene expression on endothelial cells isolated from human normal and malignant colorectal tissues. Further experiments verified TEM7 was highly expressed in the endothelium of numerous other cancer types including breast, lung and brain tumors. At least four isoforms of TEM7 are known to exist, these include intracellular, secreted, and membrane-bound forms. A homologous protein, TEM7R (also known as PLXDC2), acts as a binding partner to TEM7 and is also abundantly expressed in the endothelium of malignant colorectal cancer but is absent or rare in normal colon mucosa. High expression of TEM7 is associated with metastasis and poor survival of patients with osteogenic sarcoma.

Gene ID: 57125

UniProt: Q8IUK5