CBLN1 antibody (C-Term)

Catalog No. ABIN6990561

Product Details anti-CBLN1 Antibody

Target: CBLN1 (Cerebellin 1 Precursor (CBLN1))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBLN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: Precerebellin Antibody is affinity chromatography purified via peptide column.

Immunogen: Precerebellin antibody was raised against a 16 amino acid synthetic peptide from near the carboxy- terminus human precerebellin. The immunogen is located within the last 50 amino acids of Precerebellin.

Isotype: IgG

Application Details

Application Notes: Precerebellin antibody can be used for the detection of precerebellin by Western blot at 2 - 4 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Precerebellin Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Precerebellin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CBLN1

Target: CBLN1 (Cerebellin 1 Precursor (CBLN1))

Alternative Name: Precerebellin (CBLN1 Products)

Synonyms: cbln1 antibody, zgc:92807 antibody, CBLN1 antibody, MGC145915 antibody, AI323299 antibody, cerebellin 3 precursor antibody, cerebellin 1 precursor antibody, cerebellin 1 precursor L homeolog antibody, cerebellin 1 precursor protein antibody, cbln3 antibody, cbln1 antibody, cbln1.L antibody, CBLN1 antibody, Cbln1 antibody

Background: Precerebellin Antibody: Precerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q. Cerebellin exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/pka- dependent signaling pathway, and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release. The active form of precerebellin is highly enriched in postsynaptic structures of cerebellar Purkinje cells in cartwheel neurons of the dorsal cochlear nucleus. Because precerebellin belongs to the C1q/tumor necrosis factor superfamily of secreted proteins and has similarity to adiponectin and CTRP3, it has been suggested that precerebellin posseses functions other than those already stated.

Gene ID: 869

UniProt: P23435