STRADB antibody (C-Term)

Catalog No. ABIN6990442

Product Details anti-STRADB Antibody

Target: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STRADB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Anti-ILPIP is specific for human ILPIP only.

Purification: ILPIP Antibody is affinity chromatography purified via peptide column.

Immunogen: ILPIP antibody was raised against a synthetic peptide corresponding to amino acids at the C-terminus of human ILPIP. The immunogen is located within the last 50 amino acids of ILPIP.

Isotype: IgG

Application Details

Application Notes: ILPIP antibody can be used for the detection of ILPIP by Western blot at 0.5 to 2 μ,g/mL. Aa 34 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: ILPIP Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: ILPIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for STRADB

Target: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Alternative Name: ILPIP (STRADB Products)

Background: ILPIP Antibody: ILPIP (ILP-interacting protein) has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family. Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1β, converting enzyme of Fas-induced apotosis. This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival, suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed.

Gene ID: 55437

NCBI Accession: NP_061041

UniProt: Q9C0K7

Pathways: AMPK Signaling