DRAK2 antibody (C-Term)

Catalog No. ABIN6990304

Product Details anti-DRAK2 Antibody

Target: DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRAK2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC)

Specificity: It has no cross responses to DAP or ZIP kinases. The approximately 70 kDa band is probably non-related to DRAK2 although it is peptide blockable.

Purification: DRAK2 Antibody is Ion exchange chromatography purified.

Immunogen: DRAK2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human DRAK2. The immunogen is located within the last 50 amino acids of DRAK2.

Isotype: IgG

Application Details

Application Notes: DRAK2 antibody can be used for detection of DRAK2 by Western blot 0.5 μ,g/mL. An approximately 45 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: DRAK2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: DRAK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for DRAK2

Target: DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))

Alternative Name: DRAK2 (STK17B Products)

Synonyms: zgc:65989 antibody, STK17B antibody, DRAK2 antibody, Drak2 antibody, 3110009A03Rik antibody, AI120141 antibody, serine/threonine kinase 17b (apoptosis-inducing) antibody, serine/threonine kinase 17b antibody, stk17b antibody, STK17B antibody, Stk17b antibody

Background: DRAK2 Antibody: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase-related apoptosis-inducing protein kinases). DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.

Gene ID: 9262

UniProt: O94768