CD81 antibody (N-Term)

Catalog No. ABIN6990286

Product Details anti-CD81 Antibody

Target: CD81

Binding Specificity: AA 30-80, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD81 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: CD81 Antibody is affinity chromatography purified via peptide column.

Immunogen: CD81 antibody was raised against a 20 amino acid synthetic peptide near the amino terminus of human CD81. The immunogen is located within amino acids 30 - 80 of CD81.

Isotype: IgG

Application Details

Application Notes: CD81 antibody can be used for detection of CD81 by Western blot at 2.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CD81 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CD81 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CD81

Target: CD81

Alternative Name: CD81 (CD81 Products)

Background: CD81 Antibody: CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family, a group of cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a cell surface glycoprotein that associates with integrins and appears to promote muscle cell fusion and support myotube maintenance. Along with SCARB1, LDL-R, and CLDN1, CD81 has been reported to be an entry factor for the Hepatitis C virus. Finally, recent evidence indicates that the CD81 gene is localized in a tumor-suppressor gene region and is thus a candidate gene for malignancies.

Molecular Weight: Predicted: 26 kDa

Observed: 25 kDa

Gene ID: 975

NCBI Accession: NP_004347

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C