SARS-CoV-2 (COVID-19) NSP8 Antibody is affinity chromatography purified via peptide column.
Immunogen
Anti-SARS-CoV-2 (COVID-19) NSP8 antibody was raised against a peptide corresponding to 14 amino acids near the center of SARS-CoV-2 (COVID-19) NSP8 protein. The immunogen is located within 40-90 amino acids of SARS-CoV-2 (COVID-19) NSP8.
Antibody validated: SARS-CoV-2 (COVID-19) NSP8 antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
SARS-CoV-2 (COVID-19) NSP8 Antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C,4 °C
Storage Comment
SARS-CoV-2 (COVID-19) NSP9 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
SARS-CoV-2 NSP8 (NSP8)
(SARS-CoV-2 Non-Structural Protein 8 (NSP8))
Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP8 plays a role in viral RNA synthesis (3,4,5). Forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, it may synthesize substantially longer products than oligonucleotide primers (6).