KIFAP3 antibody

Catalog No. ABIN6989655

Product Details anti-KIFAP3 Antibody

Target: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This KIFAP3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Synthetic Peptide within C-terminal human KIFAP3.

Clone: 7H10

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for KIFAP3

Target: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Alternative Name: KIFAP3 (KIFAP3 Products)

Background:

Synonyms: FLJ22818 antibody, KAP 3 antibody, KAP-3 antibody, KAP3 antibody, KIF3AP antibody, KIFA3_HUMAN antibody, Kifap3 antibody, Kinesin associated protein 3 antibody, Kinesin-associated protein 3 antibody, SMAP antibody, Smg GDS antibody, Smg GDS associated protein antibody, Smg GDS-associated protein antibody

Background: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras, one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

Gene ID: 22920

UniProt: Q92845

Pathways: Hedgehog Signaling, Sensory Perception of Sound