MXD3 antibody

Catalog No. ABIN6989617

Product Details anti-MXD3 Antibody

Target: MXD3 (MAX Dimerization Protein 3 (MXD3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MXD3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Synthetic Peptide within N-terminal human MAD3.

Clone: 11D8

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for MXD3

Target: MXD3 (MAX Dimerization Protein 3 (MXD3))

Alternative Name: MAD3 (MXD3 Products)

Synonyms: Mad3 antibody, BHLHC13 antibody, MAD3 antibody, MYX antibody, 4631412E13Rik antibody, bHLHc13 antibody, Mad antibody, zgc:66281 antibody, Myx antibody, MAX dimerization protein 3 antibody, Max dimerization protein 3 antibody, MAX dimerization protein 3 L homeolog antibody, mxd3 antibody, MXD3 antibody, Mxd3 antibody, mxd3.L antibody

Background:

Synonyms: bHLHc13 antibody, Class C basic helix-loop-helix protein 13 antibody, FLJ35523 antibody, Likely ortholog of mouse Max dimerization protein 3 antibody, MAD3_HUMAN antibody, MAX dimerization protein 3 antibody, Max dimerizer 3 antibody, Max-associated protein 3 antibody, Max-interacting transcriptional repressor MAD3 antibody, MGC2383 antibody, mxd3 antibody, Myx antibody, OTTHUMP00000223596 antibody, OTTHUMP00000223598 antibody

Background: This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008]

Gene ID: 83463

UniProt: Q9BW11