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MCFD2 antibody (AA 1-100)

MCFD2 Reactivity: Rat, Mouse WB, IF (cc), IF (p), IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6989560
  • Target See all MCFD2 Antibodies
    MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))
    Binding Specificity
    • 14
    • 7
    • 2
    • 1
    • 1
    AA 1-100
    Reactivity
    • 26
    • 22
    • 21
    Rat, Mouse
    Host
    • 29
    • 11
    Rabbit
    Clonality
    • 30
    • 10
    Polyclonal
    Conjugate
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCFD2 antibody is un-conjugated
    Application
    • 27
    • 15
    • 12
    • 12
    • 8
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse MCFD2
    Isotype
    IgG
    Top Product
    Discover our top product MCFD2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))
    Alternative Name
    MCFD2 (MCFD2 Products)
    Synonyms
    hm:zeh1186 antibody, wu:fc23b10 antibody, wu:fd50d08 antibody, zgc:103713 antibody, zgc:109915 antibody, MCFD2 antibody, DKFZp469B098 antibody, F5F8D antibody, F5F8D2 antibody, LMAN1IP antibody, SDNSF antibody, 1810021C21Rik antibody, F5f8d antibody, Lman1ip antibody, Sdnsf antibody, multiple coagulation factor deficiency 2 antibody, multiple coagulation factor deficiency 2 L homeolog antibody, MCFD2 antibody, mcfd2 antibody, mcfd2.L antibody, Mcfd2 antibody
    Background

    Synonyms: 1810021C21Rik, DKFZp686G21263, F5F8D, LMAN1IP, MCFD 2, Mcfd2, MCFD2_MOUSE, Multiple coagulation factor deficiency protein 2, Neural stem cell derived neuronal survival protein, Neural stem cell-derived neuronal survival protein, SDNSF.

    Background: This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LAMN1 (lectin mannose binding protein 1, also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D), a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jun 2010]

    Gene ID
    193813
    UniProt
    Q8K5B2
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